2022 Acura MDX vs. 2021 Lexus GX 460

2022 Acura MDX FWD


2021 Lexus GX 460
$46,900 MSRP*

Starting Price

$53,250 MSRP

Available Trim Levels

71.4 cubic feet

Maximum Cargo Capacity

64.7 cubic feet
3.5L V6 engine


4.6L V8 engine
19 mpg city / 26 mpg hwy**

EPA-Estimated MPG

15 mpg city / 19 mpg hwy
10-speed automatic transmission


6-speed automatic transmission

The 2022 Acura MDX is already making a lasting impression on local drivers, but how does it compare to a third-row SUV from a top competitor like Lexus? We think you’ll agree that our Acura MDX vs. Lexus GX 460 comparison paints a very appealing picture of the recently redesigned Acura SUV! With a lower price, a more spacious cabin, and several significant advantages in performance, the MDX is winning hearts wherever it goes.

Acura MDX vs. Lexus GX 460: Pricing and Configurations

The 2022 Acura MDX costs less than the 2021 Lexus GX 460, and the former is also available in more configurations than the latter. Here’s a closer look at the full range for both models:

2022 Acura MDX Pricing

  • 2022 Acura MDX – $46,900 MSRP*
  • 2022 Acura MDX with Technology Package – $51,600 MSRP*
  • 2022 Acura MDX with A-Spec® Package – $57,100 MSRP*
  • 2022 Acura MDX with Advance Package – $60,650 MSRP*

2021 Lexus GX 460 Pricing

  • 2021 Lexus GX 460 – $53,250 MSRP
  • 2021 Lexus GX 460 Premium – $56,340 MSRP
  • 2021 Lexus GX 460 Luxury – $64,515 MSRP

In addition, the MDX comes standard with some features that cost extra in the GX 460, including heated front seats and remote engine start! Calculate your monthly payments to find out how much you could save.

Acura MDX vs. Lexus GX 460: Interior Dimensions

The 2022 Acura MDX and the 2021 Lexus GX both offer seating for either six or seven passengers, depending on whether or not you replace the second-row bench with optional second-row captain’s chairs. However, when you really look at the numbers, it’s clear that the Acura MDX is more spacious than the Lexus GX 460:

Acura MDX vs. Lexus GX: Legroom

  • Both models offer just below 42 inches of first-row legroom and just over 29 inches of third-row legroom, butthe MDX has a much more spacious second row.
  • Second-row passengers in the Acura will have 38.5 inches of legroom. Those in the GX 460 will have just 34.1 inches.

Acura MDX vs. Lexus GX: Cargo Space

  • With all three rows of seating upright, the MDX offers 16.3 cubic feet of cargo space. That’s much more than the GX 460, which offers just 11.6 cubic feet under the same conditions.
  • At maximum, the MDX can accommodate 71.4 cubic feet. The capacity of the GX 460 tops out at 64.7 cubic feet.

Acura MDX vs. Lexus GX: Performance Features

The Lexus GX 460 comes standard with a 4.6L V8 engine that churns out 301 horsepower. That’s slightly more than you’ll find in the MDX, which carries a 3.5L V6 engine that delivers 290 hp.

However, when you’re comparing the Acura MDX vs. Lexus GX 460 on performance, you’ll need to ask yourself if you’re willing to make the following sacrifices in exchange for a meager 11-hp advantage:

  • Fuel Economy: The MDX offers EPA-estimated fuel economy of up to 19 mpg city and 26 mpg highway**. That’s much, much better than the fuel economy of the GX 460, which only offers 15 mpg city and 19 mpg highway.
  • Transmission: The Lexus GX only comes standard with a six-speed automatic transmission. That means it offers a less engaging drive than the MDX, which includes a 10-speed automatic transmission as standard.

The GX 460 comes standard with four-wheel drive, while the MDX offers front-wheel drive as standard. However, since the upgrade to Super-Handling All-Wheel Drive™ only costs $2,000, you can easily access an MDX that’s ready for anything the Manhasset and Garden City roads can throw at you.

Drivers who desire more power should be on the lookout for the Acura MDX Type S, which will offer 355 hp and 364 lb-ft of torque. Contact us if you’d like to be notified when it arrives!

Your New Acura MDX Awaits at Rallye Acura

Drivers near Roslyn and Glen Cove can find the new Acura MDX for sale or lease at our dealership. We even offer new vehicle specials to make your next upgrade that much more exciting. Schedule your test drive today!

*Prices shown are Acura suggested retail prices only and do not include taxes, license or destination and handling charge. Destination & Handling charge for sedans (excluding PMC Edition) and SUVs (excluding PMC Edition) is $1,025.00. Destination & Handling charge for PMC Edition models and NSX is $1,995.00. Acura vehicle accessory costs, labor and installation vary. Dealers set their own prices. Please consult your selected dealer.

**Based on 2022 EPA mileage ratings. Use for comparison purposes only. Your actual mileage will vary, depending on how you drive and maintain your vehicle, driving conditions, battery pack age/condition (hybrid only) and other factors.

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